bueller, in the right situation, yes, but the situation dictates it for me. I'd say somewhere around half the time I'm hunting the downwind side of doe bedding areas I either have a scent wick, scent drag or juiced mock scrape working for me. The other situation I use it religiously is when using decoys (I've come to always use a standing buck, bedding doe decoy pair when I set out decoys, which is only 2-5 times a season and in very specific situations). Take those 2 situations away and about the only other time I can think of that I use "estrus" scent is when I'm trying to get a buck to stop in a specific location in really tight quarters.
BTW, I know all about the number of captive does it would take to produce the volume of "estrus" scent sold each yr. I also am aware of the research that says you may not be able to bottle specific chemical compounds found in estrus secretions, as their half life is so short. Frankly, all I care about is if it works or not. In my honest opinion, Special Golden Estrus (fair warning, I pro staff for Wildlife Research Center) works a high enough percent for me, in those specific situations, for me not to care what is or isn't in it. All I care is if I believe it helps tilt the odds for me, and I'm completely convinced it does, in those specific situations.
To me, the key is that the buck is already looking for and actively trying to scent an estrus doe. I can't stress that enough, as can be seen by the bolded, italic, underlined text ;) If that buck is actively searching for and desperately trying to find that smell, it's soooooooooooooooooooooooooooooooooooooooo much easier to convince him your lie is real than when he's not. What's he doing cruising that downwind side of a doe bedding area? 95 out of 100 times, he's actively trying to locate an estrus doe. So, I have good luck with estrus scents there. Put that same scent drag across an alfalfa field, put a scent wick out in the woods, covering a trail between bedding and food or even between doe bedding areas, where he's more focused on getting from point A to point B and the positive responses I get drop like a rock off a cliff.
When it comes to any of these gadgets/gimmicks (scent, decoys, calling, mock scrapes, mock rubs and so on), I never use them because "this situation is setup great for calling/decoying, whatever. I use them because this is the location I believe I need to be in and one of those gadgets/gimmicks would work well here to help me tilt the scale. For example, if I'm hunting the downwind side of a doe bedding area on Halloween and have some feature pinching the downwind cruising to within bow range, I'm not using scent, period. I don't need to, as they're already going to give me a shot if they can smell the stuff anyway.
On the flip side, the stand I took what I is still one of my top 5 bucks from was different. There was nothing to pinch the bucks cruising the downwind side. So, I laid 100-150 yd long scent trail coming in. I shot him with his nose to the ground, grunting, as he followed the scent trail from somewhere out of sight that he picked it up.
All that said, I used scents up until about 4-5 yrs ago more than I do today. Back then, I was still experimenting, trying to find the sweet spots where scents work and don't work best for me. about that log ago, I believed I'd found that sweet spot and have pretty much stuck with that since. They probably play an active rool in 10 out of every 100 sits for me, if that helps quantify it. Also, I do think in general that deer scents are overhyped beyond ridiculousness, but that they can be helpful in specific situations.
I knowingly spooked 1 doe that I can remember with "estrus" scent. She crossed a scent trail on a food plot back in my experimental phase, tucked tail and ran for the woods. I "believe" it was because it was towards the end of the breeding phase, she'd already been bred and she didn't want to be harassed by the swarm of bucks that scent would attract. I could be wrong on all of that, but that was what it looked like to me.