Moles themselves don't bother fruit trees. But, if you have fruit trees near your plot, the voles can use those holes an start attacking them. Same goes for other young trees and shrubs.
When I mow my home foodplot, I get a flood of voles running for their lives. Litterally hundreds, I kill atleast a hundred with the mower deck. I have the edges of the plot mowed weekly where apple trees are planted. Only had 1 problem with voles. Uncared for cages filled with weeds was a hotel for voles. Had plum shrubs, had...... Early habitat lessons learned a decade ago. I Keep the cages clean and mowed around them, and I have no problems. Some cages do not have a fine secondary screen around the trunk, still no problems.
Moles dont bother me, voles do a bit, but not enough to act upon them. Ticks at home come more from small game and mice than the deer. Im more worried about that.