I didn't expect this level of feedback but thanks guys.
Thus far i've just filled the tank of the sprayer with the gly/water ratio from the label and driven around until I feel everything has been covered. It seems to work fine but just wanted to make sure there wasn't more to it. I've read the labels closer and might put more thought into it going forward.
Wanted to run a tank of water through the sprayer to clean it last night (is this necessary?) so I timed how long it takes to spray a full tank (15 gal). Figured with my 2 nozzle boom @ 5 MPH I can conservatively get full coverage on 0.45 acre which is about on the nuts with what a tank lasted me in practice. Going off the label mixture % of roughly 2 oz/gallon, I ended up near the often quoted 2 quart per acre, i just didn't calculate it out previously.